“Melatonin (N-acetyl-5-methoxytryptamine) is not only a pineal hormone, but also an ubiquitary molecule present in plants and part of our diet. Numerous preclinical and some clinical reports pointed to its multiple beneficial effects including oncostatic properties, and as such, it has become one of the most aspiring goals in cancer prevention/therapy. A link between cancer and inflammation and/or metabolic disorders has been well established and the therapy of these conditions with so-called pleiotropic drugs, which include non-steroidal anti-inflammatory drugs, statins and peroral antidiabetics, modulates a cancer risk too. Adjuvant therapy with melatonin may improve the oncostatic potential of these drugs. Results from preclinical studies are limited though support this hypothesis, which, however, remains to be verified by further research.”
Read the full study here: https://www.mdpi.com/1422-0067/19/12/3910
Light pollution is one of the main causes of suppressed melatonin.
So instead of just supplementing way, we want to look into our lifestyle and things that may mess with our melatonin production, such as blue light. Our melatonin production is critical, as this hormone can not only suppress cancer cell growth, but also cause cancer cell death. Melatonin reaches hormone producing glands, such as the ovaries and the pituitary gland, and stops the production of their hormones: estrogen, progesterone, follicle stimulating hormone (F.S.H.), and the lutenizing hormone (L.H.). These can cause rapid breast tissue cell replication. It is the cellular replication and turnover that increases the risk of transcription (or genetic copying) errors to occur in their genetic coding, and copying errors can lead to cancer.
With hormones it is all about balance - not too much, not too little.
And to achieve that balance, we need a balanced overall lifestyle, as boring as that may sound. Our hormones never lie: if we are stressed out, over-training, starving ourselves, not sleeping and eating right, this will show up in our hormone lab work (I recommend testing saliva or via dutch method for accurate measure of active hormones only). And out-of-whack hormones increases our risk of cancer along with a slew of other things.